PUBLICAÇÕES
Artigos e publicações selecionadas de autoria dos membros vigentes do LABE.
2022
2021
RUIZ, GABRIEL PALERMO ; CAMARA, HENRIQUE ; FAZOLINI, NARAYANA P.B. ; Mori, Marcelo A. . Extracellular miRNAs in redox signaling: health, disease and potential therapies. FREE RADICAL BIOLOGY AND MEDICINE, v. online, p. online, 2021.
2020
Brandão BB, Madsen S, Rabiee A, Oliverio M, Ruiz GP, Ferrucci DL, Branquinho JL, Razolli D, Pinto S, Nielsen TS, Festuccia WT, Martins AS, Guerra BA, Knittel TL, Søgaard D, Larsen S, Helge JW, Brandauer J, Velloso LA, Emanuelli B, Kornfeld JW, Kahn CR, Vienberg SG, Zierath JR, Treebak JT, Mori MA. Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23932-23941. doi: 10.1073/pnas.2011243117. Epub 2020 Sep 8. PMID: 32900951; PMCID: PMC7519274.
BRAGA, DEISI L.; MOUSOVICH-NETO, FELIPPE; TONON-DA-SILVA, GUILHERME; SALGUEIRO, WILLIAN G.; MORI, MARCELO A.. Epigenetic changes during ageing and their underlying mechanisms. BIOGERONTOLOGY, v. 21, n. 4, SI, APR 2020. Web of Science Citations: 1. (18/11792-9, 17/01184-9, 18/11672-3, 19/14391-8, 17/08829-5, 17/22057-5)
MARCELO A. MORI. Aging: a New Perspective on an Old Issue. Anais da Academia Brasileira de Ciências, v. 92, n. 2, p. -, 2020. Web of Science Citations: 0. (17/25583-0, 17/01184-9)
TOWNSEND, LOGAN K. ; BRUNETTA, BRUNETTA S ; Mori, Marcelo A. . Mitochondria-associated ER membranes in glucose homeostasis and insulin resistance. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. online, p. ajpendo.00271.2020, 2020.
ROCHA, ANDRÉA LIVIA ; DE LIMA, TANES IMAMURA ; DE SOUZA, GERSON PROFETA ; CORRÊA, RENAN OLIVEIRA ; FERRUCCI, DANILO LOPES ; RODRIGUES, BRUNO ; LOPES-RAMOS, CAMILA ; NILSSON, DANIEL ; KNITTEL, THIAGO LEITE ; CASTRO, POLLYANA RIBEIRO ; FERNANDES, MARIANE FONT ; DOS SANTOS MARTINS, FLAVIANO ; PARMIGIANI, RAPHAEL BESSA ; SILVEIRA, LEONARDO REIS ; CARVALHO, HERNANDES F. ; AUWERX, JOHAN ; VINOLO, MARCO AURÉLIO R. ; Boucher, Jeremie ; Mori, Marcelo A. . Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression. SCIENCE ADVANCES, v. 6, p. eabc6250, 2020.
2019
MORI, MARCELO A.; LUDWIG, RAISSA G.; GARCIA-MARTIN, RUBEN; BRANDAO, BRUNA B.; KAHN, C. RONALD. Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease. Cell Metabolism, v. 30, n. 4, p. 656-673, OCT 1 2019. Web of Science Citations: 3. (17/07975-8, 17/01184-9, 17/23920-9)
MORI, MARCELO A.; LUDWIG, RAISSA G.; GARCIA-MARTIN, RUBEN; BRANDAO, BRUNA B.; KAHN, C. RONALD. Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease. Cell Metabolism, v. 30, n. 4, p. 656-673, OCT 1 2019. Web of Science Citations: 3. (17/07975-8, 17/01184-9, 17/23920-9)
PEREIRA, CATIA M.; FILEV, RENATO; DUBIELA, FRANCISCO P.; BRANDAO, BRUNA B.; QUEIROZ, CLAUDIO M.; LUDWIG, RAISSA G.; HIPOLIDE, DEBORA; LONGO, BEATRIZ M.; MELLO, LUIZ E.; MORI, MARCELO A.; et al. The GCN2 inhibitor IMPACT contributes to diet-induced obesity and body temperature control. PLoS One, v. 14, n. 6, JUN 5 2019. Web of Science Citations: 0. (09/52047-5, 12/04079-8)
DE-SOUZA, EVANDRO A ; CAMARA, HENRIQUE ; SALGUEIRO, WILLIAN G ; MORO, RAÍSSA P ; KNITTEL, THIAGO L ; TONON, GUILHERME ; PINTO, SILAS ; PINCA, ANA PAULA F ; ANTEBI, ADAM ; PASQUINELLI, AMY E ; MASSIRER, KATLIN B ; Mori, Marcelo A . RNA interference may result in unexpected phenotypes in Caenorhabditis elegans. NUCLEIC ACIDS RESEARCH, v. online, p. online, 2019.
GUERRA, BEATRIZ A. ; BRANDAO, B. B. ; PINTO, S. ; SALGUEIRO, W. G. ; SOUZA, E. A. ; REIS, F. C. G. ; BATISTA, T. M. ; CAVALCANTI-SILVA, V. ; D¿Almeida, Vânia ; CASTILHO, B. A. ; CARNEIRO, E. M. ; ANTEBI, A. ; FESTUCCIA, W. ; Mori, Marcelo A . Dietary Sulfur Amino Acid Restriction Upregulates DICER to Confer Beneficial Effects. Molecular Metabolism, v. 29, p. 124, 2019.
2018
OTTON, ROSEMARI; BOLIN, ANAYSA PAOLA; FERREIRA, LETICIA TORRES; MARINOVIC, MARCELO PARADISO; SILVA ROCHA, ANDREA LIVIA; MORI, MARCELO ALVES. Polyphenol-rich green tea extract improves adipose tissue metabolism by down-regulating miR-335 expression and mitigating insulin resistance and inflammation. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, v. 57, p. 170-179, JUL 2018. Web of Science Citations: 11. (13/22293-0, 15/01316-7)
LUDWIG, RAISSA G.; ROCHA, ANDREA L.; MORI, MARCELO A.. Circulating molecules that control brown/beige adipocyte differentiation and thermogenic capacity. Cell Biology International, v. 42, n. 6, SI, p. 701-710, JUN 2018. Web of Science Citations: 1. (17/07975-8, 15/01316-7, 17/01184-9, 16/12294-7, 15/20822-0)
Mori, Marcelo A.. Editorial: Non-Coding RNAs: Entwining Metabolism and Aging. Frontiers in Endocrinology, v. 9, p. 9, 2018.
PINTO, SILAS ; SATO, VITOR N. ; DE-SOUZA, EVANDRO A. ; FERRAZ, RAFAEL C. ; CAMARA, HENRIQUE ; PINCA, ANA PAULA F. ; MAZZOTTI, DIEGO R. ; LOVCI, MICHAEL T. ; TONON, GUILHERME ; LOPES-RAMOS, CAMILA M. ; PARMIGIANI, RAPHAEL B. ; Wurtele, Martin ; MASSIRER, KATLIN B. ; Mori, Marcelo A. . Enoxacin Extends Lifespan of C. elegans by Inhibiting miR-34-5p and Promoting Mitohormesis. Redox Biology, v. 18, p. 84, 2018.
2017
Brandão BB, Guerra BA, Mori MA. Shortcuts to a functional adipose tissue: The role of small non-coding RNAs. Redox Biol. 2017 Aug;12:82-102. doi: 10.1016/j.redox.2017.01.020
2016
Ferraz RC, Camara H, De-Souza EA, Pinto S, Pinca APF, Silva, Sato VN, Castilho BA, Mori MA. IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans. BMC Biology. 2016 Oct 7. 14:87; doi: 10.1186/s12915-016-0301-2
Reis FCG, Branquinho JLO, Brandão BB, Guerra BB, Silva ID, Frontini A, Thomou T, Sartini L, Cinti S, Kahn CR, Festuccia WT, Kowaltowski AJ, Mori MA. Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice. Aging (Albany, NY). 2016 May 28; doi: 10.18632/aging.100970
Oliverio M; Schmidt E, Mauer J, Baitzel C, Hansmeier NR, Khani S, Konieczka S, Pradas-Juni M, Brodesser S, Van T, Bartsch D, Bronneke HS, Heine M, Hilpert H, Tarcitano E, Garinis G, Frommolt P, Heeren J, Mori MA, Kornfeld J. Dicer1–miR-328–Bace1 signalling controls brown adipose tissue differentiation and function. Nature Cell Biology. 2016 Feb 22; doi: 10.1038/ncb3316
2014
Mori MA, Thomou T, Boucher J, Lee KY, Lallukka S, Kim JK, Torriani M, Yki-Järvinen H, Grinspoon SK, Cypess AM, Kahn CR. Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy. J Clin Invest. 2014 Jul 1. pii: 73468. doi: 10.1172/JCI73468.
2013
Kleinridders A, Lauritzen HP, Ussar S, Christensen JH, Mori MA, Bross P, Kahn CR. Leptin regulation of Hsp60 impacts hypothalamic insulin signaling. J Clin Invest. 2013 Oct 1.
Cypess AM, White AP, Vernochet C, Schulz TJ, Xue R, Sass CA, Huang TL, Roberts-Toler C, Weiner LS, Sze C, Chacko AT, Deschamps LN, Herder LM, Truchan N, Glasgow AL, Holman AR, Gavrila A, Hasselgren PO, Mori MA, Molla M, Tseng YH. Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat Med. 2013 May;19(5):635-9.
Lee KY, Russell SJ, Ussar S, Boucher J, Vernochet C, Mori MA, Smyth G, Rourk M, Cederquist C, Rosen ED, Kahn BB, Kahn CR. Lessons on conditional gene targeting in mouse adipose tissue. Diabetes. 2013 Mar;62(3):864-74.
2012
Mori MA, Raghavan P, Thomou T, Boucher J, Robida-Stubbs S, Macotela Y, Russell SJ, Kirkland JL, Blackwell TK, Kahn CR. Role of microRNA processing in adipose tissue in stress defense and longevity. Cell Metab. 2012 Sep 5;16(3):336-47.
Mori MA, Sales VM, Motta FL, Fonseca RG, Alenina N, Guadagnini D, Schadock I, Silva ED, Torres HA, Dos Santos EL, Castro CH, D'Almeida V, Andreotti S, Campaña AB, Sertié RA, Saad MJ, Lima FB, Bader M, Pesquero JB. Kinin b(1) receptor in adipocytes regulates glucose tolerance and predisposition to obesity. PLoS One. 2012;7(9):e44782.
Boucher J, Mori MA, Lee KY, Smyth G, Liew CW, Macotela Y, Rourk M, Bluher M, Russell SJ, Kahn CR. Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling. Nat Commun. 2012 Jun 12;3:902.
Macotela Y, Emanuelli B, Mori MA, Gesta S, Schulz TJ, Tseng YH, Kahn CR. Intrinsic differences in adipocyte precursor cells from different white fat depots. Diabetes. 2012 Jul;61(7):1691-9.
2011
Sun L, Xie H, Mori MA, Alexander R, Yuan B, Hattangadi SM, Liu Q, Kahn CR, Lodish HF. Mir193b-365 is essential for brown fat differentiation. Nat Cell Biol. 2011 Jul 10;13(8):958-65.